Host adaptive immunity alters gut microbiota
نویسندگان
چکیده
منابع مشابه
Gut Microbiota Co-microevolution with Selection for Host Humoral Immunity
To explore coevolution between the gut microbiota and the humoral immune system of the host, we used chickens as the model organism. The host populations were two lines (HAS and LAS) developed from a common founder that had undergone 40 generations of divergent selection for antibody titers to sheep red blood cells (SRBC) and two relaxed sublines (HAR and LAR). Analysis revealed that microevolu...
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Recurrent infections are very common in children and a major challenge for pediatricians. They affect the children’s quality of life, cause absences from school and lost parental working days, and repeated medical examinations, hospital admissions as well as antibiotic therapies lead to high costs for society. Given their prevalence and clinical importance, various prevention strategies have be...
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Healthy individuals live in peaceful co-existence with an immense load of intestinal bacteria. This symbiosis is advantageous for both the host and the bacteria. For the host it provides access to otherwise undigestible nutrients and colonization resistance against pathogens. In return the bacteria receive an excellent nutrient habitat. The mucosal immune adaptations to the presence of this com...
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The composition and activity of the gut microbiota codevelop with the host from birth and is subject to a complex interplay that depends on the host genome, nutrition, and life-style. The gut microbiota is involved in the regulation of multiple host metabolic pathways, giving rise to interactive host-microbiota metabolic, signaling, and immune-inflammatory axes that physiologically connect the ...
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The endogenous intestinal microbiota represents the multitudes of microbes residing in the intestine and is integral in multiple physiological processes of the host, including being a key factor involved in host metabolism, BW, and energy homeostasis. The gut microflora, together with other environmental factors such as diet and stress, can play a central role in both immune and nutritional phy...
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ژورنال
عنوان ژورنال: The ISME Journal
سال: 2014
ISSN: 1751-7362,1751-7370
DOI: 10.1038/ismej.2014.165